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Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus

[Image: see text] Ribonucleotide reductase (RNR) is an essential enzyme with a complex mechanism of allosteric regulation found in nearly all living organisms. Class I RNRs are composed of two proteins, a large α-subunit (R1) and a smaller β-subunit (R2) that exist as homodimers, that combine to for...

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Detalles Bibliográficos
Autores principales: Rehling, Daniel, Scaletti, Emma Rose, Rozman Grinberg, Inna, Lundin, Daniel, Sahlin, Margareta, Hofer, Anders, Sjöberg, Britt-Marie, Stenmark, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772380/
https://www.ncbi.nlm.nih.gov/pubmed/34941255
http://dx.doi.org/10.1021/acs.biochem.1c00503