Cargando…

Lack of Type I Interferon Signaling Ameliorates Respiratory Syncytial Virus-Induced Lung Inflammation and Restores Antioxidant Defenses

Respiratory syncytial virus (RSV) infection in mouse and human lung is associated with pathogenic inflammation and oxidative injury. RSV impairs antioxidant responses by increasing the degradation of transcription factor NF-E2-related factor 2 (NRF2), which controls the expression of several antioxi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ansar, Maria, Qu, Yue, Ivanciuc, Teodora, Garofalo, Roberto P., Casola, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772717/
https://www.ncbi.nlm.nih.gov/pubmed/35052571
http://dx.doi.org/10.3390/antiox11010067