The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients with Myelofibrosis

Myelofibrosis (MF) is the Philadelphia-negative myeloproliferative neoplasm characterized by the worst prognosis and no response to conventional therapy. Driver mutations in JAK2 and CALR impact on JAK-STAT pathway activation but also on the production of reactive oxygen species (ROS). ROS play a pi...

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Detalles Bibliográficos
Autores principales: Genovese, Elena, Mirabile, Margherita, Rontauroli, Sebastiano, Sartini, Stefano, Fantini, Sebastian, Tavernari, Lara, Maccaferri, Monica, Guglielmelli, Paola, Bianchi, Elisa, Parenti, Sandra, Carretta, Chiara, Mallia, Selene, Castellano, Sara, Colasante, Corrado, Balliu, Manjola, Bartalucci, Niccolò, Palmieri, Raffaele, Ottone, Tiziana, Mora, Barbara, Potenza, Leonardo, Passamonti, Francesco, Voso, Maria Teresa, Luppi, Mario, Vannucchi, Alessandro Maria, Tagliafico, Enrico, Manfredini, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772737/
https://www.ncbi.nlm.nih.gov/pubmed/35052617
http://dx.doi.org/10.3390/antiox11010113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772737/
https://www.ncbi.nlm.nih.gov/pubmed/35052617
http://dx.doi.org/10.3390/antiox11010113

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