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Screening of the Promising Direct Thrombin Inhibitors from Haematophagous Organisms. Part I: Recombinant Analogues and Their Antithrombotic Activity In Vitro

The success in treatment of venous thromboembolism and acute coronary syndromes using direct thrombin inhibitors has stimulated research aimed at finding a new anticoagulant from haematophagous organisms. This study deals with the comparison between hirudin-1 from Hirudomedicinalis(desirudin), being...

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Detalles Bibliográficos
Autores principales: Kostromina, Maria A., Tukhovskaya, Elena A., Shaykhutdinova, Elvira R., Slashcheva, Gulsara A., Ismailova, Alina M., Palikov, Victor A., Palikova, Yuliya A., Dyachenko, Igor A., Kravchenko, Irina N., Sadovnikova, Elena S., Novikova, Nadezhda I., Perepechenova, Natalia A., Zayats, Evgeniy A., Abramchik, Yuliya A., Lykoshin, Dmitry D., Mamaev, Andrey N., Grigorieva, Elena V., Momot, Andrey P., Murashev, Arkady N., Esipov, Roman S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772750/
https://www.ncbi.nlm.nih.gov/pubmed/35052692
http://dx.doi.org/10.3390/biomedicines10010011