NRF2 Activation Ameliorates Oxidative Stress and Improves Mitochondrial Function and Synaptic Plasticity, and in A53T α-Synuclein Hippocampal Neurons

In Parkinson’s disease (PD), brain oxidative stress and mitochondrial dysfunction contribute to neuronal loss as well as motor and cognitive deficits. The transcription factor NRF2 has emerged as a promising therapeutic target in PD because it sits at the intersection of antioxidant and mitochondria...

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Detalles Bibliográficos
Autores principales: Brandes, Mikah S., Zweig, Jonathan A., Tang, Anita, Gray, Nora E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772776/
https://www.ncbi.nlm.nih.gov/pubmed/35052530
http://dx.doi.org/10.3390/antiox11010026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772776/
https://www.ncbi.nlm.nih.gov/pubmed/35052530
http://dx.doi.org/10.3390/antiox11010026

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