Effect of Different Piperacillin-Tazobactam Dosage Regimens on Synergy of the Combination with Tobramycin against Pseudomonas aeruginosa for the Pharmacokinetics of Critically Ill Patients in a Dynamic Infection Model

We evaluated piperacillin-tazobactam and tobramycin regimens against Pseudomonas aeruginosa isolates from critically ill patients. Static-concentration time-kill studies (SCTK) assessed piperacillin-tazobactam and tobramycin monotherapies and combinations against four isolates over 72 h. A 120 h-dyn...

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Detalles Bibliográficos
Autores principales: Tait, Jessica R., Bilal, Hajira, Rogers, Kate E., Lang, Yinzhi, Kim, Tae-Hwan, Zhou, Jieqiang, Wallis, Steven C., Bulitta, Jürgen B., Kirkpatrick, Carl M. J., Paterson, David L., Lipman, Jeffrey, Bergen, Phillip J., Roberts, Jason A., Nation, Roger L., Landersdorfer, Cornelia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772788/
https://www.ncbi.nlm.nih.gov/pubmed/35052977
http://dx.doi.org/10.3390/antibiotics11010101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772788/
https://www.ncbi.nlm.nih.gov/pubmed/35052977
http://dx.doi.org/10.3390/antibiotics11010101

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