Inducible T-Cell Costimulator Ligand Plays a Dual Role in Melanoma Metastasis upon Binding to Osteopontin or Inducible T-Cell Costimulator

Recently, we demonstrated that inducible T-cell costimulator (ICOS) shares its unique ligand (ICOSL) with osteopontin (OPN), and OPN/ICOSL binding promotes tumor metastasis and angiogenesis in the 4T1 breast cancer model. Literature showed that OPN promotes melanoma metastasis by suppressing T-cell...

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Detalles Bibliográficos
Autores principales: Raineri, Davide, Cappellano, Giuseppe, Vilardo, Beatrice, Maione, Federica, Clemente, Nausicaa, Canciani, Elena, Boggio, Elena, Gigliotti, Casimiro Luca, Monge, Chiara, Dianzani, Chiara, Boldorini, Renzo, Dianzani, Umberto, Chiocchetti, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772802/
https://www.ncbi.nlm.nih.gov/pubmed/35052731
http://dx.doi.org/10.3390/biomedicines10010051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772802/
https://www.ncbi.nlm.nih.gov/pubmed/35052731
http://dx.doi.org/10.3390/biomedicines10010051

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