Approaching Sites of Action of Temozolomide for Pharmacological and Clinical Studies in Glioblastoma

Temozolomide (TMZ), together with bulk resection and focal radiotherapy, is currently a standard of care for glioblastoma. Absorption, distribution, metabolism, and excretion (ADME) parameters, together with the mode of action of TMZ, make its biochemical and biological action difficult to understan...

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Detalles Bibliográficos
Autores principales: Fresnais, Margaux, Turcan, Sevin, Theile, Dirk, Ungermann, Johannes, Abou Zeed, Yasmin, Lindner, Joshua Raoul, Breitkopf, Marius, Burhenne, Jürgen, Haefeli, Walter E., Longuespée, Rémi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772814/
https://www.ncbi.nlm.nih.gov/pubmed/35052681
http://dx.doi.org/10.3390/biomedicines10010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772814/
https://www.ncbi.nlm.nih.gov/pubmed/35052681
http://dx.doi.org/10.3390/biomedicines10010001

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