Overexpression of NOX2 Exacerbates AngII-Mediated Cardiac Dysfunction and Metabolic Remodelling

The present study aimed to examine the effects of low doses of angiotensin II (AngII) on cardiac function, myocardial substrate utilization, energetics, and mitochondrial function in C57Bl/6J mice and in a transgenic mouse model with cardiomyocyte specific upregulation of NOX2 (csNOX2 TG). Mice were...

Descripción completa

Detalles Bibliográficos
Autores principales: Hansen, Synne S., Pedersen, Tina M., Marin, Julie, Boardman, Neoma T., Shah, Ajay M., Aasum, Ellen, Hafstad, Anne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772838/
https://www.ncbi.nlm.nih.gov/pubmed/35052647
http://dx.doi.org/10.3390/antiox11010143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772838/
https://www.ncbi.nlm.nih.gov/pubmed/35052647
http://dx.doi.org/10.3390/antiox11010143

Ejemplares similares