Cargando…
Overexpression of NOX2 Exacerbates AngII-Mediated Cardiac Dysfunction and Metabolic Remodelling
The present study aimed to examine the effects of low doses of angiotensin II (AngII) on cardiac function, myocardial substrate utilization, energetics, and mitochondrial function in C57Bl/6J mice and in a transgenic mouse model with cardiomyocyte specific upregulation of NOX2 (csNOX2 TG). Mice were...
Autores principales: | Hansen, Synne S., Pedersen, Tina M., Marin, Julie, Boardman, Neoma T., Shah, Ajay M., Aasum, Ellen, Hafstad, Anne D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772838/ https://www.ncbi.nlm.nih.gov/pubmed/35052647 http://dx.doi.org/10.3390/antiox11010143 |
Ejemplares similares
-
Isolated perfused working hearts provide valuable additional information during phenotypic assessment of the diabetic mouse heart
por: Pedersen, Tina M., et al.
Publicado: (2018) -
How Exercise May Amend Metabolic Disturbances in Diabetic Cardiomyopathy
por: Hafstad, Anne D., et al.
Publicado: (2015) -
NADPH Oxidase 2 Mediates Myocardial Oxygen Wasting in Obesity
por: Hafstad, Anne D., et al.
Publicado: (2020) -
3-Weeks of Exercise Training Increases Ischemic-Tolerance in Hearts From High-Fat Diet Fed Mice
por: Boardman, Neoma T., et al.
Publicado: (2019) -
Cardiac Fibroblast-Specific Knockout of PGC-1α Accelerates AngII-Induced Cardiac Remodeling
por: Chen, Hong-jin, et al.
Publicado: (2021)