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Hypochlorite-Modified LDL Induces Arrhythmia and Contractile Dysfunction in Cardiomyocytes

Neutrophil-derived myeloperoxidase (MPO) and its potent oxidant, hypochlorous acid (HOCl), gained attention as important oxidative mediators in cardiac damage and dysfunction. As cardiomyocytes generate low-density lipoprotein (LDL)-like particles, we aimed to identify the footprints of proatherogen...

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Detalles Bibliográficos
Autores principales: Koyani, Chintan N., Scheruebel, Susanne, Jin, Ge, Kolesnik, Ewald, Zorn-Pauly, Klaus, Mächler, Heinrich, Hoefler, Gerald, von Lewinski, Dirk, Heinzel, Frank R., Pelzmann, Brigitte, Malle, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772905/
https://www.ncbi.nlm.nih.gov/pubmed/35052529
http://dx.doi.org/10.3390/antiox11010025