Experimental and Molecular Docking Studies of Cyclic Diphenyl Phosphonates as DNA Gyrase Inhibitors for Fluoroquinolone-Resistant Pathogens

DNA gyrase and topoisomerase IV are proven to be validated targets in the design of novel antibacterial drugs. In this study, we report the antibacterial evaluation and molecular docking studies of previously synthesized two series of cyclic diphenylphosphonates (1a–e and 2a–e) as DNA gyrase inhibit...

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Detalles Bibliográficos
Autores principales: Saleh, Neveen M., Moemen, Yasmine S., Mohamed, Sara H., Fathy, Ghady, Ahmed, Abdullah A. S., Al-Ghamdi, Ahmed A., Ullah, Sami, El Sayed, Ibrahim El-Tantawy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772930/
https://www.ncbi.nlm.nih.gov/pubmed/35052930
http://dx.doi.org/10.3390/antibiotics11010053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772930/
https://www.ncbi.nlm.nih.gov/pubmed/35052930
http://dx.doi.org/10.3390/antibiotics11010053

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