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Age-Related Mitochondrial Impairment and Renal Injury Is Ameliorated by Sulforaphane via Activation of Transcription Factor NRF2

Age is one of the major risk factors for the development of chronic pathologies, including kidney diseases. Oxidative stress and mitochondrial dysfunction play a pathogenic role in aging kidney disease. Transcription factor NRF2, a master regulator of redox homeostasis, is altered during aging, but...

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Detalles Bibliográficos
Autores principales: Mohammad, Razia Sultana, Lokhandwala, Mustafa F., Banday, Anees A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772968/
https://www.ncbi.nlm.nih.gov/pubmed/35052660
http://dx.doi.org/10.3390/antiox11010156