Enoxaparin and Pentosan Polysulfate Bind to the SARS-CoV-2 Spike Protein and Human ACE2 Receptor, Inhibiting Vero Cell Infection

As with many other pathogens, SARS-CoV-2 cell infection is strongly dependent on the interaction of the virus-surface Spike protein with the glycosaminoglycans of target cells. The SARS-CoV-2 Spike glycoprotein was previously shown to interact with cell-surface-exposed heparan sulfate and heparin in...

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Detalles Bibliográficos
Autores principales: Ennemoser, Maria, Rieger, Julia, Muttenthaler, Eva, Gerlza, Tanja, Zatloukal, Kurt, Kungl, Andreas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772983/
https://www.ncbi.nlm.nih.gov/pubmed/35052728
http://dx.doi.org/10.3390/biomedicines10010049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772983/
https://www.ncbi.nlm.nih.gov/pubmed/35052728
http://dx.doi.org/10.3390/biomedicines10010049

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