Iron Inhibits the Translation and Activity of the Renal Epithelial Sodium Channel

SIMPLE SUMMARY: Here, we investigated the regulation of the renal epithelial sodium channel (ENaC) by iron in two established cell lines and a transgenic animal model of iron overload. We show that iron availability inhibits ENaC protein expression and its activity. We provide a discussion for putat...

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Detalles Bibliográficos
Autores principales: Alli, Abdel A., Yu, Ling, Wlazlo, Ewa, Kasem, Sadat, Gholam, Mohammed F., Desai, Dhruv, Lugo, Carlos I., Vaulont, Sophie, Scindia, Yogesh M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772986/
https://www.ncbi.nlm.nih.gov/pubmed/35053120
http://dx.doi.org/10.3390/biology11010123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772986/
https://www.ncbi.nlm.nih.gov/pubmed/35053120
http://dx.doi.org/10.3390/biology11010123

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