Impaired Brain Mitochondrial Bioenergetics in the Ts65Dn Mouse Model of Down Syndrome Is Restored by Neonatal Treatment with the Polyphenol 7,8-Dihydroxyflavone

Down syndrome (DS), a major genetic cause of intellectual disability, is characterized by numerous neurodevelopmental defects. Previous in vitro studies highlighted a relationship between bioenergetic dysfunction and reduced neurogenesis in progenitor cells from the Ts65Dn mouse model of DS, suggest...

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Detalles Bibliográficos
Autores principales: Valenti, Daniela, Stagni, Fiorenza, Emili, Marco, Guidi, Sandra, Bartesaghi, Renata, Vacca, Rosa Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773005/
https://www.ncbi.nlm.nih.gov/pubmed/35052567
http://dx.doi.org/10.3390/antiox11010062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773005/
https://www.ncbi.nlm.nih.gov/pubmed/35052567
http://dx.doi.org/10.3390/antiox11010062

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