Glycan Activation of Clec4b Induces Reactive Oxygen Species Protecting against Neutrophilia and Arthritis

Animal models for complex diseases are needed to position and analyze the function of interacting genes. Previous positional cloning identified Ncf1 and Clec4b to be major regulators of arthritis models in rats. Here, we investigate epistasis between Ncf1 and Clec4b, two major regulators of arthriti...

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Detalles Bibliográficos
Autores principales: Aoun, Mike, Cai, Xiaojie, Xu, Bingze, Lahore, Gonzalo Fernandez, Bonner, Michael Yi, He, Yibo, Bäckdahl, Liselotte, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773064/
https://www.ncbi.nlm.nih.gov/pubmed/35052516
http://dx.doi.org/10.3390/antiox11010012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773064/
https://www.ncbi.nlm.nih.gov/pubmed/35052516
http://dx.doi.org/10.3390/antiox11010012

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