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Fine Tuning of an Oxidative Stress Model with Sodium Iodate Revealed Protective Effect of NF-κB Inhibition and Sex-Specific Difference in Susceptibility of the Retinal Pigment Epithelium

Oxidative stress of the retinal pigment epithelium (RPE) is a major risk factor for age-related macular degeneration (AMD). As a dry AMD model via oxidative stress, sodium iodate (NaIO(3)), which is primarily toxic to the RPE, has often been used at a high dose to cause RPE death for studying photor...

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Detalles Bibliográficos
Autores principales: Yang, Xue, Rai, Usha, Chung, Jin-Yong, Esumi, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773095/
https://www.ncbi.nlm.nih.gov/pubmed/35052607
http://dx.doi.org/10.3390/antiox11010103