Cargando…

Prophylactic Activation of Shh Signaling Attenuates TBI-Induced Seizures in Zebrafish by Modulating Glutamate Excitotoxicity through Eaat2a

Approximately 2 million individuals experience a traumatic brain injury (TBI) every year in the United States. Secondary injury begins within minutes after TBI, with alterations in cellular function and chemical signaling that contribute to excitotoxicity. Post-traumatic seizures (PTS) are experienc...

Descripción completa

Detalles Bibliográficos
Autores principales: Hentig, James, Campbell, Leah J., Cloghessy, Kaylee, Lee, Mijoon, Boggess, William, Hyde, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773121/
https://www.ncbi.nlm.nih.gov/pubmed/35052712
http://dx.doi.org/10.3390/biomedicines10010032