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Prophylactic Activation of Shh Signaling Attenuates TBI-Induced Seizures in Zebrafish by Modulating Glutamate Excitotoxicity through Eaat2a
Approximately 2 million individuals experience a traumatic brain injury (TBI) every year in the United States. Secondary injury begins within minutes after TBI, with alterations in cellular function and chemical signaling that contribute to excitotoxicity. Post-traumatic seizures (PTS) are experienc...
Autores principales: | Hentig, James, Campbell, Leah J., Cloghessy, Kaylee, Lee, Mijoon, Boggess, William, Hyde, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773121/ https://www.ncbi.nlm.nih.gov/pubmed/35052712 http://dx.doi.org/10.3390/biomedicines10010032 |
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