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DNA Damage Repair: Predictor of Platinum Efficacy in Ovarian Cancer?

Ovarian cancer (OC) is the seventh most common type of cancer in women worldwide. Treatment for OC usually involves a combination of surgery and chemotherapy with carboplatin and paclitaxel. Platinum-based agents exert their cytotoxic action through development of DNA damage, including the formation...

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Detalles Bibliográficos
Autores principales: Stefanou, Dimitra T., Souliotis, Vassilis L., Zakopoulou, Roubini, Liontos, Michalis, Bamias, Aristotelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773153/
https://www.ncbi.nlm.nih.gov/pubmed/35052761
http://dx.doi.org/10.3390/biomedicines10010082