Development of Small-Molecule STING Activators for Cancer Immunotherapy

In cancer immunotherapy, the cyclic GMP–AMP synthase–stimulator of interferon genes (STING) pathway is an attractive target for switching the tumor immunophenotype from ‘cold’ to ‘hot’ through the activation of the type I interferon response. To develop a new chemical entity for STING activator to i...

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Detalles Bibliográficos
Autores principales: Jung, Hee Ra, Jo, Seongman, Jeon, Min Jae, Lee, Hyelim, Chu, Yeonjeong, Lee, Jeehee, Kim, Eunha, Song, Gyu Yong, Jung, Cheulhee, Kim, Hyejin, Lee, Sanghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773171/
https://www.ncbi.nlm.nih.gov/pubmed/35052713
http://dx.doi.org/10.3390/biomedicines10010033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773171/
https://www.ncbi.nlm.nih.gov/pubmed/35052713
http://dx.doi.org/10.3390/biomedicines10010033

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