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In Vitro Anticancer Activity and Mechanism of Action of an Aziridinyl Galactopyranoside

We recently screened a series of new aziridines β-D-galactopyranoside derivatives for selective anticancer activity and identified 2-methyl-2,3-[N-(4-methylbenzenesulfonyl)imino]propyl 2,3-di-O-benzyl-4,6-O-(S)-benzylidene-β-D-galactopyranoside (AzGalp) as the most promising compound. In this articl...

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Detalles Bibliográficos
Autores principales: Burgos-Morón, Estefanía, Pastor, Nuria, Orta, Manuel Luis, Jiménez-Alonso, Julio José, Palo-Nieto, Carlos, Vega-Holm, Margarita, Vega-Pérez, José Manuel, Iglesias-Guerra, Fernando, Mateos, Santiago, López-Lázaro, Miguel, Calderón-Montaño, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773213/
https://www.ncbi.nlm.nih.gov/pubmed/35052721
http://dx.doi.org/10.3390/biomedicines10010041