Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction

TAR DNA-binding protein 43 (TDP-43) is a member of an evolutionarily conserved family of heterogeneous nuclear ribonucleoproteins that modulate multiple steps in RNA metabolic processes. Cytoplasmic aggregation of TDP-43 in affected neurons is a pathological hallmark of many neurodegenerative diseas...

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Detalles Bibliográficos
Autores principales: Jeon, Yu-Mi, Kwon, Younghwi, Lee, Shinrye, Kim, Seyeon, Jo, Myungjin, Lee, Seongsoo, Kim, Sang Ryong, Kim, Kiyoung, Kim, Hyung-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773243/
https://www.ncbi.nlm.nih.gov/pubmed/35052586
http://dx.doi.org/10.3390/antiox11010082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773243/
https://www.ncbi.nlm.nih.gov/pubmed/35052586
http://dx.doi.org/10.3390/antiox11010082

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