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3-Formylchromone Counteracts STAT3 Signaling Pathway by Elevating SHP-2 Expression in Hepatocellular Carcinoma

SIMPLE SUMMARY: STAT3 acts as a potential tumor-promoting transcription factor that gets aberrantly activated in several types of human cancers and plays a crucial role in tumor progression and metastasis. STAT3 expression has been correlated with a dismal prognosis and poor survival. In this study,...

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Detalles Bibliográficos
Autores principales: Mohan, Chakrabhavi Dhananjaya, Yang, Min Hee, Rangappa, Shobith, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Alahmadi, Tahani Awad, Deivasigamani, Amudha, Hui, Kam Man, Sethi, Gautam, Rangappa, Kanchugarakoppal S., Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773260/
https://www.ncbi.nlm.nih.gov/pubmed/35053027
http://dx.doi.org/10.3390/biology11010029