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Saccharin Stimulates Insulin Secretion Dependent on Sweet Taste Receptor-Induced Activation of PLC Signaling Axis

Background: Saccharin is a common artificial sweetener and a bona fide ligand for sweet taste receptors (STR). STR can regulate insulin secretion in beta cells, so we investigated whether saccharin can stimulate insulin secretion dependent on STR and the activation of phospholipase C (PLC) signaling...

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Detalles Bibliográficos
Autores principales: Serrano, Joan, Meshram, Nishita N., Soundarapandian, Mangala M., Smith, Kathleen R., Mason, Carter, Brown, Ian S., Tyrberg, Björn, Kyriazis, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773316/
https://www.ncbi.nlm.nih.gov/pubmed/35052799
http://dx.doi.org/10.3390/biomedicines10010120