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The Effect of Coenzyme Q10 on Liver Injury Induced by Valproic Acid and Its Antiepileptic Activity in Rats

Valproic acid (VPA) has toxic metabolites that can elevate oxidative stress markers, and the hepatotoxicity of VPA has been reported. Coenzyme Q10 (CoQ10) is one of the most widely used antioxidants. The effect of CoQ10 on epileptogenesis and VPA hepatotoxicity were examined. Rats were randomly divi...

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Detalles Bibliográficos
Autores principales: Alqarni, Fahad, Eweis, Hala S., Ali, Ahmed, Alrafiah, Aziza, Alsieni, Mohammed, Karim, Shahid, Alkathyri, Mosleh Ayed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773341/
https://www.ncbi.nlm.nih.gov/pubmed/35052847
http://dx.doi.org/10.3390/biomedicines10010168