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Rapamycin Suppresses Penile NADPH Oxidase Activity to Preserve Erectile Function in Mice Fed a Western Diet

The mechanistic target of rapamycin (mTOR) is a nutrient-sensitive cellular signaling kinase that has been implicated in the excess production of reactive oxygen species (ROS). NADPH oxidase-derived ROS have been implicated in erectile dysfunction pathogenesis. The objective of this study was to det...

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Detalles Bibliográficos
Autores principales: La Favor, Justin D., Pierre, Clifford J., Bivalacqua, Trinity J., Burnett, Arthur L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773370/
https://www.ncbi.nlm.nih.gov/pubmed/35052748
http://dx.doi.org/10.3390/biomedicines10010068