Trimethylamine N-Oxide Promotes Autoimmunity and a Loss of Vascular Function in Toll-like Receptor 7-Driven Lupus Mice

Plasma levels of trimethylamine N-oxide (TMAO) are elevated in lupus patients. We analyzed the implication of TMAO in autoimmunity and vascular dysfunction of the murine model of systemic lupus erythematosus (SLE) induced by the activation of the Toll-like receptor (TLR)7 with imiquimod (IMQ). Femal...

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Detalles Bibliográficos
Autores principales: González-Correa, Cristina, Moleón, Javier, Miñano, Sofía, de la Visitación, Néstor, Robles-Vera, Iñaki, Gómez-Guzmán, Manuel, Jiménez, Rosario, Romero, Miguel, Duarte, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773414/
https://www.ncbi.nlm.nih.gov/pubmed/35052589
http://dx.doi.org/10.3390/antiox11010084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773414/
https://www.ncbi.nlm.nih.gov/pubmed/35052589
http://dx.doi.org/10.3390/antiox11010084

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