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Metabolic Adaptions/Reprogramming in Islet Beta-Cells in Response to Physiological Stimulators—What Are the Consequences

Irreversible pancreatic β-cell damage may be a result of chronic exposure to supraphysiological glucose or lipid concentrations or chronic exposure to therapeutic anti-diabetic drugs. The β-cells are able to respond to blood glucose in a narrow concentration range and release insulin in response, fo...

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Detalles Bibliográficos
Autores principales: Newsholme, Philip, Rowlands, Jordan, Rose’Meyer, Roselyn, Cruzat, Vinicius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773416/
https://www.ncbi.nlm.nih.gov/pubmed/35052612
http://dx.doi.org/10.3390/antiox11010108