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Insulin-like Growth Factor II Prevents MPP+ and Glucocorticoid Mitochondrial-Oxidative and Neuronal Damage in Dopaminergic Neurons

Stress seems to contribute to Parkinson’s disease (PD) neuropathology, probably by dysregulation of the hypothalamic–pituitary–adrenal axis. Key factors in this pathophysiology are oxidative stress and mitochondrial dysfunction and neuronal glucocorticoid-induced toxicity. The insulin-like growth fa...

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Detalles Bibliográficos
Autores principales: Claros, Silvia, Cabrera, Pablo, Valverde, Nadia, Romero-Zerbo, Silvana Y., López-González, Manuel Víctor, Shumilov, Kirill, Rivera, Alicia, Pavia, Jose, Martín-Montañez, Elisa, Garcia-Fernandez, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773450/
https://www.ncbi.nlm.nih.gov/pubmed/35052545
http://dx.doi.org/10.3390/antiox11010041