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Insulin-like Growth Factor II Prevents MPP+ and Glucocorticoid Mitochondrial-Oxidative and Neuronal Damage in Dopaminergic Neurons
Stress seems to contribute to Parkinson’s disease (PD) neuropathology, probably by dysregulation of the hypothalamic–pituitary–adrenal axis. Key factors in this pathophysiology are oxidative stress and mitochondrial dysfunction and neuronal glucocorticoid-induced toxicity. The insulin-like growth fa...
Autores principales: | Claros, Silvia, Cabrera, Pablo, Valverde, Nadia, Romero-Zerbo, Silvana Y., López-González, Manuel Víctor, Shumilov, Kirill, Rivera, Alicia, Pavia, Jose, Martín-Montañez, Elisa, Garcia-Fernandez, María |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773450/ https://www.ncbi.nlm.nih.gov/pubmed/35052545 http://dx.doi.org/10.3390/antiox11010041 |
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