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HIF-1 and NRF2; Key Molecules for Malignant Phenotypes of Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer progression involves interactions between cancer cells and stromal cells in harsh tumor microenvironments, which are characterized by hypoxia, few nutrients, and oxidative stress. Clinically, cancer cells overcome therapeutic interventions, such as chemotherapy and...

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Detalles Bibliográficos
Autores principales: Hamada, Shin, Matsumoto, Ryotaro, Masamune, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773475/
https://www.ncbi.nlm.nih.gov/pubmed/35053572
http://dx.doi.org/10.3390/cancers14020411