Restoring FAS Expression via Lipid-Encapsulated FAS DNA Nanoparticle Delivery Is Sufficient to Suppress Colon Tumor Growth In Vivo

SIMPLE SUMMARY: A key feature of human colorectal tumor is loss of FAS expression. FAS is the death receptor for FASL of activated T cells. Loss of FAS expression therefore may promote tumor cell immune escape. We aimed at determining whether restoring FAS expression is sufficient to suppress colore...

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Detalles Bibliográficos
Autores principales: Merting, Alyssa D., Poschel, Dakota B., Lu, Chunwan, Klement, John D., Yang, Dafeng, Li, Honglin, Shi, Huidong, Chapdelaine, Eric, Montgomery, Mitzi, Redman, Michael T., Savage, Natasha M., Nayak-Kapoor, Asha, Liu, Kebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773494/
https://www.ncbi.nlm.nih.gov/pubmed/35053524
http://dx.doi.org/10.3390/cancers14020361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773494/
https://www.ncbi.nlm.nih.gov/pubmed/35053524
http://dx.doi.org/10.3390/cancers14020361

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