ATX-101, a Peptide Targeting PCNA, Has Antitumor Efficacy Alone or in Combination with Radiotherapy in Murine Models of Human Glioblastoma

SIMPLE SUMMARY: PCNA is an interesting target for cancertreatment due to its essential activities in DNA replication and repair and its recently discovered regulatory roles in cellular signaling. Here, we demonstrate that ATX-101, a peptide targeting PCNA, has antitumor effects as a single agent and...

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Detalles Bibliográficos
Autores principales: Gravina, Giovanni Luca, Colapietro, Alessandro, Mancini, Andrea, Rossetti, Alessandra, Martellucci, Stefano, Ventura, Luca, Di Franco, Martina, Marampon, Francesco, Mattei, Vincenzo, Biordi, Leda Assunta, Otterlei, Marit, Festuccia, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773508/
https://www.ncbi.nlm.nih.gov/pubmed/35053455
http://dx.doi.org/10.3390/cancers14020289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773508/
https://www.ncbi.nlm.nih.gov/pubmed/35053455
http://dx.doi.org/10.3390/cancers14020289

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