Nuclear Localization of BRAF(V600E) Is Associated with HMOX-1 Upregulation and Aggressive Behavior of Melanoma Cells

SIMPLE SUMMARY: Despite some successes of selective anti-BRAF(V600E) inhibitors, resistance remains a major challenge. The aim of our study is to determine the role of nuclear BRAF(V600E) and its newly identified partner, HMOX1, in melanoma aggressiveness and drug resistance. We identified the mecha...

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Detalles Bibliográficos
Autores principales: Zerfaoui, Mourad, Toraih, Eman, Ruiz, Emmanuelle, Errami, Youssef, Attia, Abdallah S., Krzysztof, Moroz, Abd Elmageed, Zakaria Y., Kandil, Emad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773521/
https://www.ncbi.nlm.nih.gov/pubmed/35053476
http://dx.doi.org/10.3390/cancers14020311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773521/
https://www.ncbi.nlm.nih.gov/pubmed/35053476
http://dx.doi.org/10.3390/cancers14020311

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