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The Role of COA6 in the Mitochondrial Copper Delivery Pathway to Cytochrome c Oxidase

Copper is essential for the stability and activity of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain. Copper is bound to COX1 and COX2, two core subunits of CcO, forming the Cu(B) and Cu(A) sites, respectively. Biogenesis of these two copper sites of CcO occur...

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Detalles Bibliográficos
Autores principales: Swaminathan, Abhinav B., Gohil, Vishal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773535/
https://www.ncbi.nlm.nih.gov/pubmed/35053273
http://dx.doi.org/10.3390/biom12010125