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Molecular Mechanisms in Pentanucleotide Repeat Diseases

The number of neurodegenerative diseases resulting from repeat expansion has increased extraordinarily in recent years. In several of these pathologies, the repeat can be transcribed in RNA from both DNA strands producing, at least, one toxic RNA repeat that causes neurodegeneration by a complex mec...

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Detalles Bibliográficos
Autores principales: Loureiro, Joana R., Castro, Ana F., Figueiredo, Ana S., Silveira, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773600/
https://www.ncbi.nlm.nih.gov/pubmed/35053321
http://dx.doi.org/10.3390/cells11020205