Systemic Injection of Oncolytic Vaccinia Virus Suppresses Primary Tumor Growth and Lung Metastasis in Metastatic Renal Cell Carcinoma by Remodeling Tumor Microenvironment

Immune checkpoint inhibitors and tyrosine kinase inhibitors are the first-line treatment for metastatic renal cell carcinoma (mRCC), but their benefits are limited to specific patient subsets. Here, we aimed to evaluate the therapeutic efficacy of JX-594 (pexastimogene devacirepvec, Pexa-vec) monoth...

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Detalles Bibliográficos
Autores principales: Park, Jee Soo, Lee, Myung Eun, Jang, Won Sik, Kim, Jongchan, Park, Se Mi, Oh, Keunhee, Lee, Namhee, Ham, Won Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773601/
https://www.ncbi.nlm.nih.gov/pubmed/35052851
http://dx.doi.org/10.3390/biomedicines10010173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773601/
https://www.ncbi.nlm.nih.gov/pubmed/35052851
http://dx.doi.org/10.3390/biomedicines10010173

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