Cargando…

Synthesis of C2-Alkoxy-Substituted 19-Nor Vitamin D(3) Derivatives: Stereoselectivity and Biological Activity

The active form of vitamin D(3) (D(3)), 1a,25-dihydroxyvitamn D(3) (1,25D(3)), plays a central role in calcium and bone metabolism. Many structure–activity relationship (SAR) studies of D(3) have been conducted, with the aim of separating the biological activities of 1,25D(3) or reducing its side ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Mizumoto, Yuka, Sakamoto, Ryota, Nagata, Akiko, Sakane, Suzuka, Kittaka, Atsushi, Odagi, Minami, Tera, Masayuki, Nagasawa, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773602/
https://www.ncbi.nlm.nih.gov/pubmed/35053217
http://dx.doi.org/10.3390/biom12010069