Connexons Coupling to Gap Junction Channel: Potential Role for Extracellular Protein Stabilization Centers

Connexin (Cx) proteins establish intercellular gap junction channels (Cx GJCs) through coupling of two apposed hexameric Cx hemichannels (Cx HCs, connexons). Pre- and post-GJ interfaces consist of extracellular EL1 and EL2 loops, each with three conserved cysteines. Previously, we reported that know...

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Detalles Bibliográficos
Autores principales: Héja, László, Simon, Ágnes, Szabó, Zsolt, Kardos, Julianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773650/
https://www.ncbi.nlm.nih.gov/pubmed/35053197
http://dx.doi.org/10.3390/biom12010049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773650/
https://www.ncbi.nlm.nih.gov/pubmed/35053197
http://dx.doi.org/10.3390/biom12010049

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