Effects of Delivering Guanidinoacetic Acid or Its Prodrug to the Neural Tissue: Possible Relevance for Creatine Transporter Deficiency

The creatine precursor guanidinoacetate (GAA) was used as a dietary supplement in humans with no adverse events. Nevertheless, it has been suggested that GAA is epileptogenic or toxic to the nervous system. However, increased GAA content in rodents affected by guanidinoacetate methyltransferase (GAM...

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Detalles Bibliográficos
Autores principales: Adriano, Enrico, Salis, Annalisa, Damonte, Gianluca, Millo, Enrico, Balestrino, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773658/
https://www.ncbi.nlm.nih.gov/pubmed/35053827
http://dx.doi.org/10.3390/brainsci12010085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773658/
https://www.ncbi.nlm.nih.gov/pubmed/35053827
http://dx.doi.org/10.3390/brainsci12010085

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