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The Mucolipin TRPML2 Channel Enhances the Sensitivity of Multiple Myeloma Cell Lines to Ibrutinib and/or Bortezomib Treatment

Multiple myeloma (MM) is a haematological B cell malignancy characterised by clonal proliferation of plasma cells and their accumulation in the bone marrow. The aim of the present study is the evaluation of biological effects of Ibrutinib in human MM cell lines alone or in combination with different...

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Detalles Bibliográficos
Autores principales: Santoni, Giorgio, Amantini, Consuelo, Maggi, Federica, Marinelli, Oliviero, Santoni, Matteo, Morelli, Maria Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773734/
https://www.ncbi.nlm.nih.gov/pubmed/35053255
http://dx.doi.org/10.3390/biom12010107