Activation of STAT and SMAD Signaling Induces Hepcidin Re-Expression as a Therapeutic Target for β-Thalassemia Patients

Iron homeostasis is regulated by hepcidin, a hepatic hormone that controls dietary iron absorption and plasma iron concentration. Hepcidin binds to the only known iron export protein, ferroportin (FPN), which regulates its expression. The major factors that implicate hepcidin regulation include iron...

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Detalles Bibliográficos
Autores principales: Saad, Hanan Kamel M., Abd Rahman, Alawiyah Awang, Ab Ghani, Azly Sumanty, Taib, Wan Rohani Wan, Ismail, Imilia, Johan, Muhammad Farid, Al-Wajeeh, Abdullah Saleh, Al-Jamal, Hamid Ali Nagi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773737/
https://www.ncbi.nlm.nih.gov/pubmed/35052868
http://dx.doi.org/10.3390/biomedicines10010189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773737/
https://www.ncbi.nlm.nih.gov/pubmed/35052868
http://dx.doi.org/10.3390/biomedicines10010189

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