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Interfacial Peptides as Affinity Modulating Agents of Protein-Protein Interactions
The identification of disease-related protein-protein interactions (PPIs) creates objective conditions for their pharmacological modulation. The contact area (interfaces) of the vast majority of PPIs has some features, such as geometrical and biochemical complementarities, “hot spots”, as well as an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773757/ https://www.ncbi.nlm.nih.gov/pubmed/35053254 http://dx.doi.org/10.3390/biom12010106 |