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Interfacial Peptides as Affinity Modulating Agents of Protein-Protein Interactions

The identification of disease-related protein-protein interactions (PPIs) creates objective conditions for their pharmacological modulation. The contact area (interfaces) of the vast majority of PPIs has some features, such as geometrical and biochemical complementarities, “hot spots”, as well as an...

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Detalles Bibliográficos
Autores principales: Ershov, Pavel V., Mezentsev, Yuri V., Ivanov, Alexis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773757/
https://www.ncbi.nlm.nih.gov/pubmed/35053254
http://dx.doi.org/10.3390/biom12010106