Cargando…

Interfacial Peptides as Affinity Modulating Agents of Protein-Protein Interactions

The identification of disease-related protein-protein interactions (PPIs) creates objective conditions for their pharmacological modulation. The contact area (interfaces) of the vast majority of PPIs has some features, such as geometrical and biochemical complementarities, “hot spots”, as well as an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ershov, Pavel V., Mezentsev, Yuri V., Ivanov, Alexis S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773757/ https://www.ncbi.nlm.nih.gov/pubmed/35053254 http://dx.doi.org/10.3390/biom12010106

Ejemplares similares

Uncharacterized Proteins CxORFx: Subinteractome Analysis and Prognostic Significance in Cancers
por: Ershov, Pavel, et al.
Publicado: (2023)

Protein Interactome Profiling of Stable Molecular Complexes in Biomaterial Lysate
por: Mezentsev, Yuri, et al.
Publicado: (2022)

SPR Biosensors in Direct Molecular Fishing: Implications for Protein Interactomics
por: Florinskaya, Anna, et al.
Publicado: (2018)

Mechanism of the Affinity-Enhancing Effect of Isatin on Human Ferrochelatase and Adrenodoxin Reductase Complex Formation: Implication for Protein Interactome Regulation
por: Ershov, Pavel V., et al.
Publicado: (2020)

Affinity Isolation and Mass Spectrometry Identification of Prostacyclin Synthase (PTGIS) Subinteractome
por: Ershov, Pavel V., et al.
Publicado: (2019)

Prostanoid Signaling in Cancers: Expression and Regulation Patterns of Enzymes and Receptors
por: Ershov, Pavel V., et al.
Publicado: (2022)

Enzymes in the Cholesterol Synthesis Pathway: Interactomics in the Cancer Context
por: Ershov, Pavel, et al.
Publicado: (2021)

SARS-COV-2 Coronavirus Papain-like Protease PLpro as an Antiviral Target for Inhibitors of Active Site and Protein–Protein Interactions
por: Ershov, P. V., et al.
Publicado: (2023)

Molecular Cloning, Heterologous Expression, Purification, and Evaluation of Protein–Ligand Interactions of CYP51 of Candida krusei Azole-Resistant Fungal Strain
por: Tsybruk, Tatsiana V., et al.
Publicado: (2023)

Modulators of protein–protein interactions as antimicrobial agents
por: Kahan, Rashi, et al.
Publicado: (2021)

Studying protein–protein affinity and immobilized ligand–protein affinity interactions using MS-based methods
por: Kool, Jeroen, et al.
Publicado: (2011)

Approaching infinite affinity through engineering of peptide–protein interaction
por: Keeble, Anthony H., et al.
Publicado: (2019)

PPI-Affinity: A Web Tool for the Prediction and Optimization of Protein–Peptide and Protein–Protein Binding Affinity
por: Romero-Molina, Sandra, et al.
Publicado: (2022)

Modulating Protein–Protein Interactions by Cyclic and Macrocyclic Peptides. Prominent Strategies and Examples
por: González-Muñiz, Rosario, et al.
Publicado: (2021)

Fc-Binding Ligands of Immunoglobulin G: An Overview of High Affinity Proteins and Peptides
por: Choe, Weonu, et al.
Publicado: (2016)

On the binding affinity of macromolecular interactions: daring to ask why proteins interact
por: Kastritis, Panagiotis L., et al.
Publicado: (2013)

Quantitative FRET (qFRET) Technology for the Determination of Protein–Protein Interaction Affinity in Solution
por: Liao, Jiayu, et al.
Publicado: (2021)

How Structure Defines Affinity in Protein-Protein Interactions
por: Erijman, Ariel, et al.
Publicado: (2014)

Natural Compounds Interacting with Nicotinic Acetylcholine Receptors: From Low-Molecular Weight Ones to Peptides and Proteins
por: Kudryavtsev, Denis, et al.
Publicado: (2015)

Structure-based protein–ligand interaction fingerprints for binding affinity prediction
por: Wang, Debby D., et al.
Publicado: (2021)

An Interfacial Affinity Interaction-Based Method for Detecting HOTAIR lncRNA in Cancer Plasma Samples
por: Clack, Kimberley, et al.
Publicado: (2022)

Affinity Enhancement by Ligand Clustering Effect Inspired by Peptide Dendrimers−Shank PDZ Proteins Interactions
por: Liu, Jiahui, et al.
Publicado: (2016)

Direct Molecular Fishing of New Protein Partners for Human Thromboxane Synthase
por: Svirid, A. V., et al.
Publicado: (2017)

Peptide‐based covalent inhibitors of protein–protein interactions
por: Paulussen, Felix M., et al.
Publicado: (2022)

Analysis of Proteins and Peptides of Highly Purified CD9(+) and CD63(+) Horse Milk Exosomes Isolated by Affinity Chromatography
por: Sedykh, Sergey E., et al.
Publicado: (2022)

Analysis of drug interactions with serum proteins and related binding agents by affinity capillary electrophoresis: A review
por: Sharmeen, Sadia, et al.
Publicado: (2022)

Protein-Protein Interactions of Tandem Affinity Purified Protein Kinases from Rice
por: Rohila, Jai S., et al.
Publicado: (2009)

Study of the Interfacial Interaction Performance of Branched Bonding Agents and CL-20
por: Zhao, Yanmei, et al.
Publicado: (2019)

Artificial Affinity Proteins as Ligands of Immunoglobulins
por: Mouratou, Barbara, et al.
Publicado: (2015)

Polymer effects modulate binding affinities in disordered proteins
por: Vancraenenbroeck, Renee, et al.
Publicado: (2019)

Redesigning Protein Cavities as a Strategy for Increasing Affinity in Protein-Protein Interaction: Interferon-γ Receptor 1 as a Model
por: Černý, Jiří, et al.
Publicado: (2015)

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)
por: Murale, Dhiraj P., et al.
Publicado: (2017)

Favourable Interfacial Characteristics of A2 Milk Protein Monolayer
por: Dhopte, Balaji S., et al.
Publicado: (2022)

Single Bead Affinity Detection (SINBAD) for the Analysis of Protein-Protein Interactions
por: Schulte, Roberta, et al.
Publicado: (2008)

The Interfacial Interactions of Glycine and Short Glycine Peptides in Model Membrane Systems
por: Doucette, Kaitlin A., et al.
Publicado: (2020)

Constrained α-Helical Peptides as Inhibitors of Protein-Protein and Protein-DNA Interactions
por: Roy, Siddhartha, et al.
Publicado: (2018)

Interfacial Interactions during Demolding in Nanoimprint Lithography
por: Li, Mingjie, et al.
Publicado: (2021)

General Approach for Characterizing In Vitro Selected Peptides with Protein Binding Affinity
por: Larsen, Andrew C., et al.
Publicado: (2014)

Branched Multimeric Peptides as Affinity Reagents for the Detection of α-Klotho Protein
por: Ye, Xiyun, et al.
Publicado: (2023)

C-Terminal Substitution of MDM2 Interacting Peptides Modulates Binding Affinity by Distinctive Mechanisms
por: Brown, Christopher J., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_hj0nv5i0a9m5jtje0p92ghhcom