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Biglycan Promotes Cancer Stem Cell Properties, NFκB Signaling and Metastatic Potential in Breast Cancer Cells

SIMPLE SUMMARY: Breast cancer stem cells (BCSCs) are a small sub-population of cells within tumors with high metastatic potential. We identified biglycan (BGN) as a prospective molecular target in BCSCs that regulates the aggressive phenotypes of these cells. These findings establish a foundation fo...

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Detalles Bibliográficos
Autores principales: Manupati, Kanakaraju, Paul, Ritama, Hao, Mingang, Haas, Michael, Bian, Zhaoqun Christine, Holm, Tammy M., Guan, Jun-Lin, Yeo, Syn Kok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773822/
https://www.ncbi.nlm.nih.gov/pubmed/35053617
http://dx.doi.org/10.3390/cancers14020455