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Signal Amplification in Highly Ordered Networks Is Driven by Geometry

Here, we hypothesize that, in biological systems such as cell surface receptors that relay external signals, clustering leads to substantial improvements in signaling efficiency. Representing cooperative signaling networks as planar graphs and applying Euler’s polyhedron formula, we can show that cl...

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Detalles Bibliográficos
Autores principales: Vanamee, Éva S., Lippner, Gábor, Faustman, Denise L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773832/
https://www.ncbi.nlm.nih.gov/pubmed/35053388
http://dx.doi.org/10.3390/cells11020272