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Early Blockade of CB1 Receptors Ameliorates Schizophrenia-like Alterations in the Neurodevelopmental MAM Model of Schizophrenia

In agreement with the neurodevelopmental hypothesis of schizophrenia, prenatal exposure of Sprague-Dawley rats to the antimitotic agent methylazoxymethanol acetate (MAM) at gestational day 17 produces long-lasting behavioral alterations such as social withdrawal and cognitive impairment in adulthood...

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Detalles Bibliográficos
Autores principales: Stark, Tibor, Iannotti, Fabio Arturo, Di Martino, Serena, Di Bartolomeo, Martina, Ruda-Kucerova, Jana, Piscitelli, Fabiana, Wotjak, Carsten T., D’Addario, Claudio, Drago, Filippo, Di Marzo, Vincenzo, Micale, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773886/
https://www.ncbi.nlm.nih.gov/pubmed/35053256
http://dx.doi.org/10.3390/biom12010108