Transient Exposure of Endothelial Cells to Doxorubicin Leads to Long-Lasting Vascular Endothelial Growth Factor Receptor 2 Downregulation

Doxorubicin (Dox) is an effective antineoplastic drug with serious cardiotoxic side effects that persist after drug withdrawal and can lead to heart failure. Dysregulation of vascular endothelium has been linked to the development of Dox-induced cardiotoxicity, but it is unclear whether and how tran...

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Detalles Bibliográficos
Autores principales: Graziani, Silvia, Scorrano, Luca, Pontarin, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773916/
https://www.ncbi.nlm.nih.gov/pubmed/35053325
http://dx.doi.org/10.3390/cells11020210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773916/
https://www.ncbi.nlm.nih.gov/pubmed/35053325
http://dx.doi.org/10.3390/cells11020210

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